The MIOT Centre for Children’s Cardiac Care provides comprehensive care for children with congenital and rheumatic heart disease. It is a global referral centre for neonates, including babies born pre-term and underweight. The Centre’s specialists perform highly complex and cutting-edge, open and interventional procedures on its little patients in advanced facilities that are on par with the world’s best. The MIOT Centre for Children’s Cardiac Care has revolutionised cardiac care for children in the southern part of India and set the standards for other healthcare institutions. The Centre’s specialists routinely perform a number of complex procedures on their young patients, including day-old babies, with outstanding results. Complex anomalies like pulmonary atresia, congenitally-corrected transposition of great arteries, and valve repairs, are done here. MCCC has also achieved excellent results in minimally-invasive surgery in children, where open-heart procedures are performed through mini-sternotomy incisions and thoracotomies. CHIME, in collaboration with the MIOT Centre for Children’s Cardiac Care (MCCC) in Chennai, India, has been a lifeline for children with congenital and rheumatic heart diseases. Over the past 17 years, this partnership has successfully facilitated more than 1,300 cardiac surgeries, offering critical care to many children from lower economic families who are unable to afford necessary medical treatment.